Package: RTSA Type: Package Title: 'Trial Sequential Analysis' for Error Control and Inference in Sequential Meta-Analyses Authors@R: c( person(given = "Anne", family = "Lyngholm Soerensen", email = "lynganne@gmail.com", role = c('aut', 'cre', 'trl')), person(given = "Markus", family = "Harboe Olsen", email = "markus.harboe.olsen@regionh.dk", role = c('aut', 'ctr')), person(given ="Theis", family ="Lange", email = "thlan@sund.ku.dk", role = c('ctr')), person(given ="Christian", family ="Gluud", email = "christian.gluud@ctu.dk", role = c('ctr'))) Version: 0.2.2 Description: Frequentist sequential meta-analysis based on 'Trial Sequential Analysis' (TSA) in programmed in Java by the Copenhagen Trial Unit (CTU). The primary function is the calculation of group sequential designs for meta-analysis to be used for planning and analysis of both prospective and retrospective sequential meta-analyses to preserve type-I-error control under sequential testing. 'RTSA' includes tools for sample size and trial size calculation for meta-analysis and core meta-analyses methods such as fixed-effect and random-effects models and forest plots. TSA is described in Wetterslev et. al (2008) . The methods for deriving the group sequential designs are based on Jennison and Turnbull (1999, ISBN:9780849303166). License: GPL (>= 2) URL: https://github.com/AnneLyng/RTSA BugReports: https://github.com/AnneLyng/RTSA/issues Imports: stats, metafor, ggplot2, scales, Rcpp (>= 0.11.0) LinkingTo: Rcpp Encoding: UTF-8 Depends: R (>= 3.5.0) LazyData: true RoxygenNote: 7.2.3 Suggests: gsDesign, CompQuadForm, dplyr, kableExtra, rmarkdown, knitr, bookdown, gridExtra, testthat (>= 3.0.0) VignetteBuilder: knitr, bookdown Config/testthat/edition: 3 Repository: https://annelyng.r-universe.dev Date/Publication: 2024-08-07 09:33:32 UTC RemoteUrl: https://github.com/annelyng/rtsa RemoteRef: HEAD RemoteSha: dc13c0b9d9413a101dfbf430bf8bcd1a6872875f NeedsCompilation: yes Packaged: 2026-07-03 13:57:36 UTC; root Author: Anne Lyngholm Soerensen [aut, cre, trl], Markus Harboe Olsen [aut, ctr], Theis Lange [ctr], Christian Gluud [ctr] Maintainer: Anne Lyngholm Soerensen