{ "_id": "6a47c1b3e06c18f0a651d34e", "Package": "RTSA", "Type": "Package", "Title": "'Trial Sequential Analysis' for Error Control and Inference in\nSequential Meta-Analyses", "Authors@R": "c(\nperson(given = \"Anne\", family = \"Lyngholm Soerensen\", email = \"lynganne@gmail.com\", role = c('aut', 'cre', 'trl')),\nperson(given = \"Markus\", family = \"Harboe Olsen\", email = \"markus.harboe.olsen@regionh.dk\", role = c('aut', 'ctr')),\nperson(given =\"Theis\", family =\"Lange\", email = \"thlan@sund.ku.dk\", role = c('ctr')),\nperson(given =\"Christian\", family =\"Gluud\", email = \"christian.gluud@ctu.dk\", role = c('ctr')))", "Version": "0.2.2", "Description": "Frequentist sequential meta-analysis based on 'Trial\nSequential Analysis' (TSA) in programmed in Java by the\nCopenhagen Trial Unit (CTU). The primary function is the\ncalculation of group sequential designs for meta-analysis to be\nused for planning and analysis of both prospective and\nretrospective sequential meta-analyses to preserve type-I-error\ncontrol under sequential testing. 'RTSA' includes tools for\nsample size and trial size calculation for meta-analysis and\ncore meta-analyses methods such as fixed-effect and\nrandom-effects models and forest plots. TSA is described in\nWetterslev et. al (2008) .\nThe methods for deriving the group sequential designs are based\non Jennison and Turnbull (1999, ISBN:9780849303166).", "License": "GPL (>= 2)", "URL": "https://github.com/AnneLyng/RTSA", "BugReports": "https://github.com/AnneLyng/RTSA/issues", "Encoding": "UTF-8", "LazyData": "true", "RoxygenNote": "7.2.3", "VignetteBuilder": "knitr, bookdown", "Config/testthat/edition": "3", "Repository": "https://annelyng.r-universe.dev", "Date/Publication": "2024-08-07 09:33:32 UTC", "RemoteUrl": "https://github.com/annelyng/rtsa", "RemoteRef": "HEAD", "RemoteSha": "dc13c0b9d9413a101dfbf430bf8bcd1a6872875f", "NeedsCompilation": "yes", "Packaged": { "Date": "2026-07-03 13:57:36 UTC", "User": "root" }, "Author": "Anne Lyngholm Soerensen [aut, cre, trl],\nMarkus Harboe Olsen [aut, ctr],\nTheis Lange [ctr],\nChristian Gluud [ctr]", "Maintainer": "Anne Lyngholm Soerensen ", "_user": "annelyng", "_type": "src", "_file": "RTSA_0.2.2.tar.gz", "_fileid": "https://r2.ropensci.org/fa21d60cbacea44276531ae1b5d36e45b6da95f47bfc8878999181c19d3d1cd7", "_filesize": 1188095, "_sha256": "fa21d60cbacea44276531ae1b5d36e45b6da95f47bfc8878999181c19d3d1cd7", "_expires": "2026-10-11T14:05:37.000Z", "_created": "2026-07-03T13:57:36.000Z", "_published": "2026-07-03T14:05:39.638Z", "_jobs": [ { "job": 85015227954, "time": 192, "config": "linux-devel-arm64", "r": "4.7.0", "check": "ERROR", "artifact": "8068421343" }, { "job": 85015227981, "time": 191, "config": "linux-devel-x86_64", "r": "4.7.0", "check": "ERROR", "artifact": "8068420074" }, { "job": 85015228038, "time": 213, "config": "linux-release-arm64", "r": "4.6.1", "check": "ERROR", "artifact": "8068428760" }, { "job": 85015227951, "time": 188, "config": "linux-release-x86_64", "r": "4.6.1", "check": "ERROR", "artifact": "8068418890" }, { "job": 85015228015, "time": 184, "config": "macos-oldrel-arm64", "r": "4.5.3", "check": "ERROR", "artifact": "8068417445" }, { "job": 85015227995, "time": 431, "config": "macos-oldrel-x86_64", "r": "4.5.3", "check": "ERROR", "artifact": "8068506554" }, { "job": 85015228022, "time": 134, "config": "macos-release-arm64", "r": "4.6.1", "check": "ERROR", "artifact": "8068400008" }, { "job": 85015227969, "time": 343, "config": "macos-release-x86_64", "r": "4.6.1", "check": "ERROR", "artifact": "8068474106" }, { "job": 85014597601, "time": 215, "config": "source", "r": "4.6.1", "check": "ERROR", "artifact": "8068352422" }, { "job": 85015227941, "time": 140, "config": "wasm-release", "r": "4.6.0", "check": "OK", "artifact": "8068402096" }, { "job": 85015228031, "time": 181, "config": "windows-devel", "r": "4.7.0", "check": "ERROR", "artifact": "8068416267" }, { "job": 85015227976, "time": 151, "config": "windows-oldrel", "r": "4.5.3", "check": "ERROR", "artifact": "8068405495" }, { "job": 85015228000, "time": 157, "config": "windows-release", "r": "4.6.1", "check": "ERROR", "artifact": "8068407979" } ], "_host": "GitHub-Actions", "_buildurl": "https://github.com/r-universe/annelyng/actions/runs/28665026001", "_status": "failure", "_upstream": "https://github.com/annelyng/rtsa", "_commit": { "id": "dc13c0b9d9413a101dfbf430bf8bcd1a6872875f", "author": "Anne Lyngholm ", "committer": "Anne Lyngholm ", "message": "Changed uniroot call and misc\n\nChange of how trials are included\n", "time": 1723023212 }, "_maintainer": { "name": "Anne Lyngholm Soerensen", "email": "lynganne@gmail.com", "login": "annelyng", "description": "PhD student at the Section of Biostatistics at the University of Copenhagen and School of Mathematical and Physical Sciences at Macquarie University. ", "uuid": 17158769 }, "_distro": "resolute", "_registered": true, "_dependencies": [ { "package": "R", "version": ">= 3.5.0", "role": "Depends" }, { "package": "Rcpp", "role": "LinkingTo" }, { "package": "stats", "role": "Imports" }, { "package": "metafor", "role": "Imports" }, { "package": "ggplot2", "role": "Imports" }, { "package": "scales", "role": "Imports" }, { "package": "Rcpp", "version": ">= 0.11.0", "role": "Imports" }, { "package": "gsDesign", "role": "Suggests" }, { "package": "CompQuadForm", "role": "Suggests" }, { "package": "dplyr", "role": "Suggests" }, { "package": "kableExtra", "role": "Suggests" }, { "package": "rmarkdown", "role": "Suggests" }, { "package": "knitr", "role": "Suggests" }, { "package": "bookdown", "role": "Suggests" }, { "package": "gridExtra", "role": "Suggests" }, { "package": "testthat", "version": ">= 3.0.0", "role": "Suggests" } ], "_owner": "annelyng", "_selfowned": true, "_usedby": 0, "_updates": [], "_tags": [], "_stars": 2, "_contributors": [ { "user": "annelyng", "count": 41, "uuid": 17158769 } ], "_userbio": { "uuid": 17158769, "type": "user", "name": "Anne Lyngholm", "followers": 5, "description": "PhD student at the Section of Biostatistics at the University of Copenhagen and School of Mathematical and Physical Sciences at Macquarie University. " }, "_downloads": { "count": 453, "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/RTSA" }, "_devurl": "https://github.com/annelyng/rtsa", "_searchresults": 42, "_topics": [ "cpp" ], "_rbuild": "4.6.1", "_assets": [ "extra/citation.cff", "extra/citation.html", "extra/citation.json", "extra/citation.txt", "extra/contents.json", "extra/readme.html", "extra/readme.md", "extra/RTSA.html", "manual.pdf" ], "_homeurl": "https://github.com/annelyng/rtsa", "_realowner": "annelyng", "_cranurl": true, "_releases": [ { "version": "0.1.0", "date": "2023-05-12" }, { "version": "0.2.0", "date": "2023-08-25" }, { "version": "0.2.1", "date": "2023-08-30" }, { "version": "0.2.2", "date": "2023-11-23" } ], "_exports": [ "boundaries", "inference", "metaanalysis", "minTrial", "ris", "RTSA" ], "_datasets": [ { "name": "coronary", "title": "Dataset of trials investigating the intensity of statin therapy on the risk of myocardial infarction or coronary death", "object": "coronary", "class": [ "data.frame" ], "fields": [ "study", "eI", "nI", "eC", "nC" ], "rows": 4, "table": true, "tojson": true }, { "name": "eds", "title": "Dataset of trials investigating the effect of carer on early supported discharge services", "object": "eds", "class": [ "data.frame" ], "fields": [ "study", "year", "mI", "sdI", "mC", "sdC", "nI", "nC" ], "rows": 9, "table": true, "tojson": true }, { "name": "perioOxy", "title": "Dataset of RCTs investigating the effect of 80% perioperative oxygen vs. 30 -35% perioperative oxygen on surgical site infection.", "object": "perioOxy", "class": [ "data.frame" ], "fields": [ "study", "eI", "eC", "nI", "nC" ], "rows": 15, "table": true, "tojson": true } ], "_help": [ { "page": "boundaries", "title": "Boundaries for group sequential designs", "topics": [ "boundaries" ] }, { "page": "coronary", "title": "Dataset of trials investigating the intensity of statin therapy on the risk of myocardial infarction or coronary death", "topics": [ "coronary" ] }, { "page": "eds", "title": "Dataset of trials investigating the effect of carer on early supported discharge services", "topics": [ "eds" ] }, { "page": "inference", "title": "Inference calculations for sequential meta-analysis", "topics": [ "inference" ] }, { "page": "metaanalysis", "title": "Fixed-effect or random-effects meta-analysis", "topics": [ "metaanalysis", "print.metaanalysis" ] }, { "page": "minTrial", "title": "Minimum number of trials needed for a specific level of power", "topics": [ "minTrial" ] }, { "page": "perioOxy", "title": "Dataset of RCTs investigating the effect of 80% perioperative oxygen vs. 30 -35% perioperative oxygen on surgical site infection.", "topics": [ "perioOxy" ] }, { "page": "plot.boundaries", "title": "Plot of boundaries for group sequential designs", "topics": [ "plot.boundaries" ] }, { "page": "plot.metaanalysis", "title": "Forestplot for metaanalysis object.", "topics": [ "plot.metaanalysis" ] }, { "page": "plot.RTSA", "title": "Plot RTSA object. Returns the R version of the original TSA plot.", "topics": [ "plot.RTSA" ] }, { "page": "ris", "title": "Calculate required sample and trials size.", "topics": [ "print.ris", "ris" ] }, { "page": "RTSA", "title": "R version of Trial Sequential Analysis. Used for designing and analysing sequential meta-analyses.", "topics": [ "print.RTSA", "RTSA" ] } ], "_readme": "https://github.com/annelyng/rtsa/raw/HEAD/README.md", "_rundeps": [ "cli", "cpp11", "digest", "farver", "ggplot2", "glue", "gtable", "isoband", "labeling", "lattice", "lifecycle", "mathjaxr", "Matrix", "metadat", "metafor", "nlme", "numDeriv", "pbapply", "R6", "RColorBrewer", "Rcpp", "rlang", "S7", "scales", "vctrs", "viridisLite", "withr" ], "_sysdeps": [ { "shlib": "libstdc++", "package": "libstdc++6", "source": "gcc", "version": "16-20260322-1ubuntu1", "name": "c++", "homepage": "http://gcc.gnu.org/", "description": "GNU Standard C++ Library v3" } ], "_score": 3.6232492903979003, "_indexed": true, "_nocasepkg": "rtsa", "_universes": [ "annelyng" ], "_binaries": [ { "r": "4.7.0", "os": "linux", "version": "0.2.2", "date": "2026-07-03T14:00:29.000Z", "distro": "resolute", "arch": "aarch64", "commit": "dc13c0b9d9413a101dfbf430bf8bcd1a6872875f", "fileid": "https://r2.ropensci.org/32f8dac97ae16e84099ea080d3bdc2fb0e65b751270c5a16e2b050816a4a5870", "status": "failure", "check": "ERROR", "buildurl": "https://github.com/r-universe/annelyng/actions/runs/28665026001" }, { "r": "4.7.0", "os": "linux", "version": "0.2.2", "date": "2026-07-03T14:00:11.000Z", "distro": "resolute", "arch": "x86_64", "commit": "dc13c0b9d9413a101dfbf430bf8bcd1a6872875f", "fileid": "https://r2.ropensci.org/912c81864db70a92f53864f48648578f9d2266660e6307420534c463c28425e0", "status": "failure", "check": "ERROR", "buildurl": "https://github.com/r-universe/annelyng/actions/runs/28665026001" }, { "r": "4.6.1", "os": "linux", "version": "0.2.2", "date": "2026-07-03T14:00:51.000Z", "distro": "resolute", "arch": "aarch64", "commit": "dc13c0b9d9413a101dfbf430bf8bcd1a6872875f", "fileid": "https://r2.ropensci.org/8eb0004847f0b9218bb63969d281147404ace0615446bff535d4b1a8f1bf4922", "status": "failure", "check": "ERROR", "buildurl": "https://github.com/r-universe/annelyng/actions/runs/28665026001" }, { "r": "4.6.1", "os": "linux", "version": "0.2.2", "date": "2026-07-03T14:00:08.000Z", "distro": "resolute", "arch": "x86_64", "commit": "dc13c0b9d9413a101dfbf430bf8bcd1a6872875f", "fileid": "https://r2.ropensci.org/95f401ec935bec2af44ee3925cb5b4cc4b1c415775b8577dee6f2df9d05a5ff8", "status": "failure", "check": "ERROR", "buildurl": "https://github.com/r-universe/annelyng/actions/runs/28665026001" }, { "r": "4.5.3", "os": "mac", "version": "0.2.2", "date": "2026-07-03T14:00:22.000Z", "arch": "aarch64", "commit": "dc13c0b9d9413a101dfbf430bf8bcd1a6872875f", "fileid": "https://r2.ropensci.org/bd893c912072ba274b96dc5e30cbaea8cc85c3ba142dca03650b1112bff52eb7", "status": "failure", "check": "ERROR", "buildurl": "https://github.com/r-universe/annelyng/actions/runs/28665026001" }, { "r": "4.5.3", "os": "mac", "version": "0.2.2", "date": "2026-07-03T14:03:22.000Z", "arch": "x86_64", "commit": "dc13c0b9d9413a101dfbf430bf8bcd1a6872875f", "fileid": "https://r2.ropensci.org/c8a317cea61747d19c12fe0152d6fc0d46e4f656de6f646867c80d949d4aabfe", "status": "failure", "check": "ERROR", "buildurl": "https://github.com/r-universe/annelyng/actions/runs/28665026001" }, { "r": "4.6.1", "os": "mac", "version": "0.2.2", "date": "2026-07-03T13:59:33.000Z", "arch": "aarch64", "commit": "dc13c0b9d9413a101dfbf430bf8bcd1a6872875f", "fileid": "https://r2.ropensci.org/79bceaf3ed375fd1d7131d7dfc391c33d6e4b4683a131ad024902c30c8017563", "status": "failure", "check": "ERROR", "buildurl": "https://github.com/r-universe/annelyng/actions/runs/28665026001" }, { "r": "4.6.1", "os": "mac", "version": "0.2.2", "date": "2026-07-03T14:01:51.000Z", "arch": "x86_64", "commit": "dc13c0b9d9413a101dfbf430bf8bcd1a6872875f", "fileid": "https://r2.ropensci.org/8e5157ffa3d065aba1c8f25a0817a7de24ed3669a74e2be45d9349ed86bbc893", "status": "failure", "check": "ERROR", "buildurl": "https://github.com/r-universe/annelyng/actions/runs/28665026001" }, { "r": "4.6.0", "os": "wasm", "version": "0.2.2", "date": "2026-07-03T14:00:16.000Z", "arch": "emscripten", "commit": "dc13c0b9d9413a101dfbf430bf8bcd1a6872875f", "fileid": "https://r2.ropensci.org/4b4e49a7bafe663ef430bca0da3abe9be6750b2d89c99e0e659331d24d4d74ff", "status": "success", "buildurl": "https://github.com/r-universe/annelyng/actions/runs/28665026001" }, { "r": "4.7.0", "os": "win", "version": "0.2.2", "date": "2026-07-03T13:59:23.000Z", "arch": "x86_64", "commit": "dc13c0b9d9413a101dfbf430bf8bcd1a6872875f", "fileid": "https://r2.ropensci.org/01a4facd6e4d813c5db5551e48598b555b043f4de159de6b40179f02857b317c", "status": "failure", "check": "ERROR", "buildurl": "https://github.com/r-universe/annelyng/actions/runs/28665026001" }, { "r": "4.5.3", "os": "win", "version": "0.2.2", "date": "2026-07-03T13:59:12.000Z", "arch": "x86_64", "commit": "dc13c0b9d9413a101dfbf430bf8bcd1a6872875f", "fileid": "https://r2.ropensci.org/cda3bbe7ff380f449bc9b729657a7e05db8c502c11050f39de5ee5613df269e4", "status": "failure", "check": "ERROR", "buildurl": "https://github.com/r-universe/annelyng/actions/runs/28665026001" }, { "r": "4.6.1", "os": "win", "version": "0.2.2", "date": "2026-07-03T13:59:18.000Z", "arch": "x86_64", "commit": "dc13c0b9d9413a101dfbf430bf8bcd1a6872875f", "fileid": "https://r2.ropensci.org/9599323297a70fe7da1137f58351ad60b33b44e95bf1293a8935cb30b06604dd", "status": "failure", "check": "ERROR", "buildurl": "https://github.com/r-universe/annelyng/actions/runs/28665026001" } ] }